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Publications

39. Tomko AM, Whynot EG, Dupré DJ. Anti-cancer properties of cannflavin A and potential synergistic effects with gemcitabine, cisplatin, and cannabinoids in bladder cancer. J Cannabis Res 2022 4, 41. https://doi.org/10.1186/s42238-022-00151-y

38. Tomko AM, Whynot EG, O’Leary LF, Dupré DJ. Anti-cancer potential of cannabis terpenes in a taxol-resistant model of breast cancer. Canadian Journal of Physiology and Pharmacology 2022 Jun 15. doi: 10.1139/cjpp-2021-0792. Online ahead of print.

37. O'Leary LF, Tomko AM, Dupré DJ. Polarity scaffolds signaling in epithelial cell permeability. Inflamm Res. 2021 70(5), 525-538 doi: 10.1007/s00011-021-01454-1

36. Tomko AM, Whynot EG, Ellis LD, Dupré DJ: Anti-Cancer Potential of Cannabinoids, Terpenes, and Flavonoids Present in Cannabis. Cancers (Basel). 2020 Jul 21;12(7):1985. doi: 10.3390/cancers12071985.

35. Tomko A, O’Leary L, Trask H, Achenbach JC, Hall SR, Goralski KB, Ellis LD and Dupré DJ: Antitumor Activity of Abnormal Cannabidiol and Its Analog O-1602 in Taxol-Resistant Preclinical Models of Breast Cancer. Frontiers in Pharmacolology, 2019 10:1124.

 

34. Martin L, Nachtigal MW, Selman T, Nguyen E, Salsman J, Dellaire G, Dupré DJ: ­Bitter taste receptors are expressed in human epithelial ovarian and prostate cancer cells and noscapine stimulation impacts cell survival, 2019 Apr;454(1-2):203-214.

33. Shin K, Chapman NA*, Sarker M, Kenward CA, Huang SK, Weatherbee-Martin N, Pandey A, Dupré DJ, Rainey JK. Bioactivity of the putative apelin proprotein expands the repertoire of apelin receptor ligands.

Biochim Biophys Acta. 2017, August; 1861(8):1901–1912.

*co-supervised student.

 

32. Young B, Nguyen E, Chedrawe M, Rainey JK, Dupré DJ: Differential Contribution of Transmembrane Domains IV, V, VI, and VII to Human Angiotensin II Type 1 Receptor Homomer Formation. Journal of Biological Chemistry 2017 Feb 24;292(8):3341-3350.

 

31. Young B, Purcell C, Kuang YQ, Charette N, Dupré DJ Superoxide Dismutase 1 Regulation of CXCR4-Mediated Signaling in Prostate Cancer Cells is Dependent on Cellular Oxidative State, Cell Physiology and Biochemistry 2015;37:2071-2084.

 

30. Li C, Zhang YJ, Dupré DJ, Kuang YQ Chemokine receptors and their interactors in HIV-1 replication: potential therapeutic targets, Receptors and Clinical Investigation 2015; 2: e1016. doi: 10.14800/rci.1016.

 

29. Chapman N, Dupré DJ, Rainey JK. The apelin receptor: Physiology, pathology, cell signalling, and ligand modulation of a peptide-activated class A GPCR. Biochem Cell Biol. 2014 Aug 20:1-10.

 

28. Laprairie RB, Bagher AM, Kelly ME, Dupré DJ, Denovan-Wright EM. Type 1 cannabinoid receptor ligands display functional selectivity in a cell culture model of striatal medium spiny projection neurons. J Biol Chem. 2014 Sep 5;289(36):24845-62.

 

27. Gillies K, Wertman J, Charette N, Dupré DJ, Anterograde trafficking of CXCR4 and CCR2 homo and heterodimers in a prostate cancer cell line. Cell Physiology and Biochemistry, 2013 Jul 5;32(1):74-85.

 

26. Langelaan DN, Reddy T, Banks AW, Dellaire G, Dupré DJ, Rainey JK. Structural features of the apelin receptor N-terminal tail and first transmembrane segment implicated in ligand binding and receptor trafficking. BBA – Biomembranes 2013 Feb 22;1828(6):1471-1483

 

25. Wertman J, Dupré DJ, G protein-coupled receptor dimers: Look like their parents, but act like teenagers! J Recept Signal Transduct Res. 2013 Jun;33(3):135-8

 

24. Dupre DJ, Rola-Pleszczynski M, Stankova J, Rescue of internalization-defective platelet-activating factor receptor function by EBP50/NHERF1. J Cell Commun Signal. 2012 Dec;6(4):205-16

 

23. Kuang YQ, Charette N, Frazer J, Holland PJ, Attwood KM, Dellaire G, Dupre DJ, Dopamine receptor interacting protein 78 acts as a molecular chaperone for chemokine receptors signaling complex organization. PLoS ONE 2012 7(7): e40522   

 

22. Hammad MM, Kuang YQ, Morse A, Dupre DJ, Rab1 interacts directly with beta2-adrenergic receptor to regulate receptor anterograde trafficking. Biological Chemistry, 2012 May 1;393(6):541-6

 

21. Deyts C, Vetrivel KS, Shepherd YM, Dupre DJ, Thinakaran G, Parent AT: Novel GalphaS-protein signaling associated with membrane-tethered APP intracellular domain. Journal of Neuroscience 2012 Feb1 32(5) 1714-1729

 

20. Kuang YQ, Pang W, Zheng YT, Dupre DJ: NHERF1 regulates gp120-induced internalization and signaling by CCR5, and HIV-1 production. European Journal of Immunology, 2012 Feb;42(2):299-310 Selected as a frontline (highlight) article

19. Charette N, Holland P, Frazer J, Allen H, Dupre DJ: Dependence on Different Rab GTPases for the Trafficking of CXCR4 and CCR5 Homo or Heterodimers Between the Endoplasmic Reticulum and Plasma Membrane in Jurkat Cells. Cellular Signalling (2011) 23, 1738–1749.

 

18. Hammad MM, Dupre DJ. Chaperones contribute to G protein coupled receptor oligomerization, but do not participate in assembly of the G protein with the receptor signaling complex. J Mol Signal. 2010 Sep 24;5(1):16.

 

17. Hammad MM, Kuang YQ, Yan R, Allen H, Dupre DJ. NA+/H+ exchanger regulatory factor-1 is involved in chemokine receptor homodimer CCR5 internalization and signal transduction, but does not affect CXCR4 homodimer or CXCR4-CCR5 heterodimer. J Biol Chem. 2010 Nov 5; 285(45):34653–34664.

 

 

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